| HGNC approved symbol | SHPRH |
| HGNC ID | HGNC:19336 |
| HGNC approved name | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase |
| Entrez gene ID | GeneID:257218 (SSTAR profile) |
| UniProt AC (human) | Q149N8 |
| UniProt ID (human) | SHPRH_HUMAN |
| Pfam domains | SNF2-rel_dom PF00176 (307-985) Linker_histone PF00538 (440-512) SHPRH_helical-1st PF21325 (1003-1099) SHPRH_helical-2nd PF21324 (1135-1361) zf-RING_UBOX PF13445 (1432-1478) Helicase_C PF00271 (1514-1622) |
| MGI symbol | Shprh |
| MGI ID | MGI:1917581 |
| UniProt AC (mouse) | Q7TPQ3 |
| UniProt ID (mouse) | SHPRH_MOUSE |
| HGNC gene family tag | RNF |
| HGNC gene family description | RING-type (C3HC4) zinc fingers |
| Function | Histone modification write cofactor |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:17130289 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:17130289 |
| Comment | SHPRH associates with PCNA, RAD18, and the ubiquitin-conjugating enzyme UBC13 (E2) and promotes methyl methanesulfonate (MMS)-induced PCNA polyubiquitination. |
| Status of entry | # |
| Expression range: | 0.0 to 91.55 |
| Mean expression: | 11.84 ± 8.59 |
| Median expression: | 9.94 |