HGNC approved symbol | SIN3B |
HGNC ID | HGNC:19354 |
HGNC approved name | SIN3 transcription regulator family member B |
Entrez gene ID | GeneID:23309 (SSTAR profile) |
UniProt AC (human) | O75182 |
UniProt ID (human) | SIN3B_HUMAN |
Pfam domains | PAH PF02671 (60-104, 182-235, 322-366) Sin3_corepress PF08295 (394-447, 435-521) Sin3a_C PF16879 (775-1081) |
MGI symbol | Sin3b |
MGI ID | MGI:107158 |
UniProt AC (mouse) | Q62141 |
UniProt ID (mouse) | SIN3B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase cofactor, TF |
Modification | Histone acetylation, TF repressor |
PMID for information on function | PMID:12670868 |
Protein complex | mSin3A |
Target molecule | histone, DNA |
Target entity | DNA motif |
HOCOMOCO TFBS model | |
Product | # |
PMID for information on target | PMID:12670868 |
Comment | Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. |
Status of entry | # |
Expression range: | 7.24 to 193.37 |
Mean expression: | 43.19 ± 21.13 |
Median expression: | 37.9 |