| HGNC approved symbol | SIRT2 |
| HGNC ID | HGNC:10886 |
| HGNC approved name | sirtuin 2 |
| Entrez gene ID | GeneID:22933
(SSTAR profile) |
| UniProt AC (human) | Q8IXJ6 |
| UniProt ID (human) | SIR2_HUMAN |
| Pfam domains | SIR2 PF02146 (84-268) |
| MGI symbol | Sirt2 |
| MGI ID | MGI:1927664 |
| UniProt AC (mouse) | Q8VDQ8 |
| UniProt ID (mouse) | SIR2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification erase, Histone modification write cofactor |
| Modification | Histone acetylation, Histone methylation |
| PMID for information on function | PMID:11427894 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K18ac, H3K56ac, H4K16ac, H4K20me1 |
| Product | H3K18, H3K56, H4K16, H4K20me2, H4K20me3 |
| PMID for information on target | PMID:11427894 |
| Comment | Sir2 =SIRT2 is an NAD-dependent histone deacetylase that mediates transcriptional silencing at mating-type loci, telomeres and ribosomal gene clusters. |
| Status of entry | # |