HGNC approved symbol | SMEK2 |
HGNC ID | HGNC:29267 |
HGNC approved name | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
Entrez gene ID | GeneID:57223 (SSTAR profile) |
UniProt AC (human) | Q5MIZ7 |
UniProt ID (human) | P4R3B_HUMAN |
Pfam domains | domain PF22972 (5-101) PP4R3 PF04802 (144-682) |
MGI symbol | Smek2 |
MGI ID | MGI:2144474 |
UniProt AC (mouse) | Q922R5 |
UniProt ID (mouse) | P4R3B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase cofactor |
Modification | Histone phosphorylation |
PMID for information on function | PMID:18614045 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AFX |
Product | # |
PMID for information on target | # |
Comment | Member of PPP4C-PPP4R2-PPP4R3B complex which dephosphorylates H2AFX. |
Status of entry | # |
Expression range: | 0.0 to 135.73 |
Mean expression: | 39.88 ± 20.42 |
Median expression: | 35.89 |