HGNC approved symbol | STK4 |
HGNC ID | HGNC:11408 |
HGNC approved name | serine/threonine kinase 4 |
Entrez gene ID | GeneID:6789 (SSTAR profile) |
UniProt AC (human) | Q13043 |
UniProt ID (human) | STK4_HUMAN |
Pfam domains | Pkinase PF00069 (31-281) Mst1_SARAH PF11629 (433-480) |
MGI symbol | Stk4 |
MGI ID | MGI:1929004 |
UniProt AC (mouse) | Q9JI11 |
UniProt ID (mouse) | STK4_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:12757711 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AS14 |
Product | H2BS14ph |
PMID for information on target | PMID:12757711 |
Comment | Mst1 =STK4 can phosphorylate H2B at S14 in vitro and in vivo, and the onset of H2B S14 phosphorylation is dependent upon cleavage of Mst1 by caspase-3. |
Status of entry | # |
Expression range: | 0.0 to 739.29 |
Mean expression: | 31.52 ± 58.44 |
Median expression: | 14.12 |