HGNC approved symbol | SUV420H1 |
HGNC ID | HGNC:24283 |
HGNC approved name | suppressor of variegation 4-20 homolog 1 (Drosophila) |
Entrez gene ID | GeneID:51111 (SSTAR profile) |
UniProt AC (human) | Q4FZB7 |
UniProt ID (human) | SV421_HUMAN |
Pfam domains | SET PF00856 (209-308) |
MGI symbol | Suv420h1 |
MGI ID | MGI:2444557 |
UniProt AC (mouse) | Q3U8K7 |
UniProt ID (mouse) | SV421_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | # |
Protein complex | # |
Target molecule | histone |
Target entity | H4K20 |
Product | H4K20me3 |
PMID for information on target | # |
Comment | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. (Annotated by similarity.) |
Status of entry | # |