HGNC approved symbol | SUV420H2 |
HGNC ID | HGNC:28405 |
HGNC approved name | suppressor of variegation 4-20 homolog 2 (Drosophila) |
Entrez gene ID | GeneID:84787 (SSTAR profile) |
UniProt AC (human) | Q86Y97 |
UniProt ID (human) | SV422_HUMAN |
Pfam domains | SET PF00856 (120-218) |
MGI symbol | Suv420h2 |
MGI ID | MGI:2385262 |
UniProt AC (mouse) | Q6Q783 |
UniProt ID (mouse) | SV422_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | # |
Protein complex | # |
Target molecule | histone |
Target entity | H4K20 |
Product | H4K20me3 |
PMID for information on target | # |
Comment | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. (Annotated by similarity.) |
Status of entry | # |