HGNC approved symbol | TAF12 |
HGNC ID | HGNC:11545 |
HGNC approved name | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
Entrez gene ID | GeneID:6883 (SSTAR profile) |
UniProt AC (human) | Q16514 |
UniProt ID (human) | TAF12_HUMAN |
Pfam domains | TFIID_20kDa PF03847 (59-126) |
MGI symbol | Taf12 |
MGI ID | MGI:1913714 |
UniProt AC (mouse) | Q8VE65 |
UniProt ID (mouse) | TAF12_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone chaperone, Histone modification write |
Modification | Histone acetylation |
PMID for information on function | PMID:10594036 |
Protein complex | PCAF, STAGA |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:10594036 |
Comment | Heterodimerization requires the alpha2 and alpha3 helices of the hTAF(II)20 histone fold and is abolished by mutations in the hydrophobic face of the hTAF(II)20 alpha2 helix. Interaction with hTAF(II)20 requires a domain of hTAF(II)135 which shows sequence homology to H2A. |
Status of entry | # |