HGNC approved symbol | TET3 |
HGNC ID | HGNC:28313 |
HGNC approved name | tet methylcytosine dioxygenase 3 |
Entrez gene ID | GeneID:200424 (SSTAR profile) |
UniProt AC (human) | O43151 |
UniProt ID (human) | TET3_HUMAN |
Pfam domains | zf-CXXC PF02008 (52-90) Tet_JBP PF12851 (986-1697) |
MGI symbol | Tet3 |
MGI ID | MGI:2446229 |
UniProt AC (mouse) | Q8BG87 |
UniProt ID (mouse) | TET3_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | DNA modification |
Modification | DNA hydroxymethylation |
PMID for information on function | PMID:23222540 |
Protein complex | # |
Target molecule | DNA |
Target entity | mC |
Product | hmC |
PMID for information on target | PMID:23222540 |
Comment | Ten eleven translocation (TET) enzymes, including TET1, TET2 and TET3, convert 5-methylcytosine to 5-hydroxymethylcytosine and regulate gene transcription. There is a direct interaction of TET2 and TET3 with O-GlcNAc transferase (OGT). |
Status of entry | # |
Expression range: | 0.0 to 99.11 |
Mean expression: | 3.7 ± 7.63 |
Median expression: | 1.4 |