HGNC approved symbol | TLE1 |
HGNC ID | HGNC:11837 |
HGNC approved name | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
Entrez gene ID | GeneID:7088 (SSTAR profile) |
UniProt AC (human) | Q04724 |
UniProt ID (human) | TLE1_HUMAN |
Pfam domains | TLE_N PF03920 (18-132) WD40 PF00400 (477-511, 531-558, 577-602, 607-644, 692-725, 739-766) |
MGI symbol | Tle1 |
MGI ID | MGI:104636 |
UniProt AC (mouse) | Q62440 |
UniProt ID (mouse) | TLE1_MOUSE |
HGNC gene family tag | WDR |
HGNC gene family description | WD repeat domain containing |
Function | Chromatin remodeling, Histone modification cofactor |
Modification | # |
PMID for information on function | PMID:9334241, PMID:17041588 |
Protein complex | # |
Target molecule | histone |
Target entity | H3 |
Product | # |
PMID for information on target | PMID:9334241, PMID:17041588 |
Comment | Native Groucho/TLE proteins interact specifically with histone H3 and not with other core histones. |
Status of entry | # |
Expression range: | 0.0 to 115.55 |
Mean expression: | 14.73 ± 14.41 |
Median expression: | 10.19 |