HGNC approved symbol | TNP1 |
HGNC ID | HGNC:11951 |
HGNC approved name | transition protein 1 (during histone to protamine replacement) |
Entrez gene ID | GeneID:7141 (SSTAR profile) |
UniProt AC (human) | P09430 |
UniProt ID (human) | STP1_HUMAN |
Pfam domains | TP1 PF02079 (1-53) |
MGI symbol | Tnp1 |
MGI ID | MGI:98784 |
UniProt AC (mouse) | P10856 |
UniProt ID (mouse) | STP1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:12743712 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:12743712 |
Comment | Distinct roles for the two major transition nuclear proteins, TP1 = STP1 and TP2 = STP2, in histone displacement, sperm nuclear shaping, chromatin condensation, and maintenance of DNA integrity have been proposed. |
Status of entry | # |
Expression range: | 0.0 to 3287.92 |
Mean expression: | 8.65 ± 156.06 |
Median expression: | 0.0 |