HGNC approved symbol | TOP2A |
HGNC ID | HGNC:11989 |
HGNC approved name | topoisomerase (DNA) II alpha 170kDa |
Entrez gene ID | GeneID:7153 (SSTAR profile) |
UniProt AC (human) | P11388 |
UniProt ID (human) | TOP2A_HUMAN |
Pfam domains | HATPase_c PF02518 (80-176) DNA_gyraseB PF00204 (265-425) Toprim PF01751 (456-562) TOPRIM_C PF16898 (574-711) DNA_topoisoIV PF00521 (713-1171) DTHCT PF08070 (1231-1511) |
MGI symbol | Top2a |
MGI ID | MGI:98790 |
UniProt AC (mouse) | Q01320 |
UniProt ID (mouse) | TOP2A_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:11062478 |
Protein complex | # |
Target molecule | DNA |
Target entity | DNA |
Product | # |
PMID for information on target | PMID:11062478 |
Comment | Histone deacetylase interacts directly with DNA topoisomerase II. |
Status of entry | # |
Expression range: | 0.0 to 665.75 |
Mean expression: | 69.08 ± 90.27 |
Median expression: | 27.55 |