HGNC approved symbol | TOP2B |
HGNC ID | HGNC:11990 |
HGNC approved name | topoisomerase (DNA) II beta 180kDa |
Entrez gene ID | GeneID:7155 (SSTAR profile) |
UniProt AC (human) | Q02880 |
UniProt ID (human) | TOP2B_HUMAN |
Pfam domains | HATPase_c PF02518 (101-197) DNA_gyraseB PF00204 (286-447) Toprim PF01751 (477-583) TOPRIM_C PF16898 (594-731) DNA_topoisoIV PF00521 (734-1193) DTHCT PF08070 (1447-1626) |
MGI symbol | Top2b |
MGI ID | MGI:98791 |
UniProt AC (mouse) | Q64511 |
UniProt ID (mouse) | TOP2B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:11062478 |
Protein complex | WINAC |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:11062478 |
Comment | Histone deacetylase interacts directly with DNA topoisomerase II. |
Status of entry | # |
Expression range: | 3.37 to 456.45 |
Mean expression: | 47.83 ± 31.02 |
Median expression: | 43.17 |