HGNC approved symbol | TRIM33 |
HGNC ID | HGNC:16290 |
HGNC approved name | tripartite motif containing 33 |
Entrez gene ID | GeneID:51592 (SSTAR profile) |
UniProt AC (human) | Q9UPN9 |
UniProt ID (human) | TRI33_HUMAN |
Pfam domains | zf-B_box PF00643 (274-310) PHD PF00628 (890-931) Bromodomain PF00439 (967-1046) |
MGI symbol | Trim33 |
MGI ID | MGI:2137357 |
UniProt AC (mouse) | Q99PP7 |
UniProt ID (mouse) | TRI33_MOUSE |
HGNC gene family tag | TRIM, PHF, RNF |
HGNC gene family description | Tripartite motif containing / Tripartite motif containing, Zinc fingers, PHD-type, RING-type (C3HC4) zinc fingers |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:23926104 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me3, H3K18ac |
Product | # |
PMID for information on target | PMID:23926104 |
Comment | TRIM33 helps recruit SMAD2/3 to chromatin via interaction of its PHD and Bromo domains with histone H3 trimethylated at lysine 9 (H3K9me3) and histone H3 acetylated at lysine 18 (H3K18ac), respectively. |
Status of entry | # |
Expression range: | 3.47 to 250.79 |
Mean expression: | 29.86 ± 20.56 |
Median expression: | 24.65 |