HGNC approved symbol | UBE2A |
HGNC ID | HGNC:12472 |
HGNC approved name | ubiquitin-conjugating enzyme E2A |
Entrez gene ID | GeneID:7319 (SSTAR profile) |
UniProt AC (human) | P49459 |
UniProt ID (human) | UBE2A_HUMAN |
Pfam domains | UQ_con PF00179 (8-143) |
MGI symbol | Ube2a |
MGI ID | MGI:102959 |
UniProt AC (mouse) | Q9Z255 |
UniProt ID (mouse) | UBE2A_MOUSE |
HGNC gene family tag | UBE2 |
HGNC gene family description | Ubiquitin-conjugating enzymes E2 |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:8797826 |
Protein complex | # |
Target molecule | histone |
Target entity | H2A, H2BK120 |
Product | H2BK120ub1 |
PMID for information on target | PMID:8797826 |
Comment | RAD6 (=UBE2) has been identified as the first ubiquitin-conjugating enzyme, able to mono- and polyubiquitinate histones 2A and 2B in vitro. |
Status of entry | # |