HGNC approved symbol | UBE2E1 |
HGNC ID | HGNC:12477 |
HGNC approved name | ubiquitin-conjugating enzyme E2E 1 |
Entrez gene ID | GeneID:7324 (SSTAR profile) |
UniProt AC (human) | P51965 |
UniProt ID (human) | UB2E1_HUMAN |
Pfam domains | UQ_con PF00179 (51-187) |
MGI symbol | Ube2e1 |
MGI ID | MGI:107411 |
UniProt AC (mouse) | P52482 |
UniProt ID (mouse) | UB2E1_MOUSE |
HGNC gene family tag | UBE2 |
HGNC gene family description | Ubiquitin-conjugating enzymes E2 |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:16307923 |
Protein complex | # |
Target molecule | histone |
Target entity | H2BK120 |
Product | H2BK120ub |
PMID for information on target | PMID:16307923 |
Comment | The human RNF20/40 complex functions as the E3 ligase and UbcH6 (=UBE2E1) as the ubiquitin E2-conjugating enzyme for histone H2B-K120 monoubiquitination. |
Status of entry | # |