HGNC approved symbol | USP11 |
HGNC ID | HGNC:12609 |
HGNC approved name | ubiquitin specific peptidase 11 |
Entrez gene ID | GeneID:8237 (SSTAR profile) |
UniProt AC (human) | P51784 |
UniProt ID (human) | UBP11_HUMAN |
Pfam domains | DUSP PF06337 (86-183) Ubiquitin_3 PF14836 (199-285) UCH PF00443 (309-927) USP7_C2 PF14533 (493-596) |
MGI symbol | Usp11 |
MGI ID | MGI:2384312 |
UniProt AC (mouse) | Q99K46 |
UniProt ID (mouse) | UBP11_MOUSE |
HGNC gene family tag | USP |
HGNC gene family description | Ubiquitin-specific peptidases |
Function | Histone modification erase cofactor |
Modification | Histone ubiquitination |
PMID for information on function | PMID:20233726 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:20233726 |
Comment | USP11 is a chromatin-associated protein and its catalytic activity is required for its genome maintenance activities. USP11 may be a DUB that functions in the DNA damage response to double-strand breaks. |
Status of entry | # |
Expression range: | 2.95 to 362.94 |
Mean expression: | 44.76 ± 42.8 |
Median expression: | 33.42 |