HGNC approved symbol | USP16 |
HGNC ID | HGNC:12614 |
HGNC approved name | ubiquitin specific peptidase 16 |
Entrez gene ID | GeneID:10600 (SSTAR profile) |
UniProt AC (human) | Q9Y5T5 |
UniProt ID (human) | UBP16_HUMAN |
Pfam domains | zf-UBP PF02148 (47-124) UCH PF00443 (197-819) |
MGI symbol | Usp16 |
MGI ID | MGI:1921362 |
UniProt AC (mouse) | Q99LG0 |
UniProt ID (mouse) | UBP16_MOUSE |
HGNC gene family tag | USP |
HGNC gene family description | Ubiquitin-specific peptidases |
Function | Histone modification erase |
Modification | Histone ubiquitination |
PMID for information on function | PMID:10077596 |
Protein complex | # |
Target molecule | histone |
Target entity | H2Aub |
Product | H2A |
PMID for information on target | PMID:10077596 |
Comment | Recombinant Ubp-M=USP16 is able to deubiquitinate histone H2A in vitro, and the phosphorylated form is also enzymatically active. |
Status of entry | # |
Expression range: | 0.0 to 302.0 |
Mean expression: | 35.36 ± 23.99 |
Median expression: | 31.56 |