HGNC approved symbol | USP17L2 |
HGNC ID | HGNC:34434 |
HGNC approved name | ubiquitin specific peptidase 17-like family member 2 |
Entrez gene ID | GeneID:377630 (SSTAR profile) |
UniProt AC (human) | Q6R6M4 |
UniProt ID (human) | U17L2_HUMAN |
Pfam domains | UCH PF00443 (81-372) |
MGI symbol | Usp17le |
MGI ID | MGI:3643640 |
UniProt AC (mouse) | Q7M764 |
UniProt ID (mouse) | U17PE_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase cofactor |
Modification | Histone ubiquitination |
PMID for information on function | PMID:21239494 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:21239494 |
Comment | SDS3 is a key component of the histone deacetylase (HDAC)-dependent Sin3A co-repressor complex, serving to maintain its HDAC activity. Both exogenous and endogenous functional interaction between deubiquitinating enzyme USP17 = USP17L2 and human SDS3 has been reported. |
Status of entry | # |