| HGNC approved symbol | USP49 |
| HGNC ID | HGNC:20078 |
| HGNC approved name | ubiquitin specific peptidase 49 |
| Entrez gene ID | GeneID:25862 (SSTAR profile) |
| UniProt AC (human) | Q70CQ1 |
| UniProt ID (human) | UBP49_HUMAN |
| Pfam domains | zf-UBP PF02148 (26-87) UCH PF00443 (253-654) |
| MGI symbol | Usp49 |
| MGI ID | MGI:2685391 |
| UniProt AC (mouse) | Q6P9L4 |
| UniProt ID (mouse) | UBP49_MOUSE |
| HGNC gene family tag | USP |
| HGNC gene family description | Ubiquitin-specific peptidases |
| Function | Histone modification erase |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:23824326 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2Bub |
| Product | H2B |
| PMID for information on target | PMID:23824326 |
| Comment | Ubiquitin-specific peptidase 49 (USP49) is a histone H2B-specific deubiquitinase and shows that H2B deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons. |
| Status of entry | # |
| Expression range: | 0.0 to 10.0 |
| Mean expression: | 0.98 ± 1.24 |
| Median expression: | 0.58 |