HGNC approved symbol | USP7 |
HGNC ID | HGNC:12630 |
HGNC approved name | ubiquitin specific peptidase 7 (herpes virus-associated) |
Entrez gene ID | GeneID:7874 (SSTAR profile) |
UniProt AC (human) | Q93009 |
UniProt ID (human) | UBP7_HUMAN |
Pfam domains | domain PF22486 (70-195) UCH PF00443 (214-518) USP7_ICP0_bdg PF12436 (620-867) USP7_C2 PF14533 (877-1086) |
MGI symbol | Usp7 |
MGI ID | MGI:2182061 |
UniProt AC (mouse) | Q6A4J8 |
UniProt ID (mouse) | UBP7_MOUSE |
HGNC gene family tag | USP |
HGNC gene family description | Ubiquitin-specific peptidases |
Function | Histone modification erase, DNA modification cofactor |
Modification | Histone ubiquitination, DNA methylation |
PMID for information on function | PMID:15749019 |
Protein complex | BCOR |
Target molecule | histone, DNA |
Target entity | H2Bub |
Product | H2B |
PMID for information on target | PMID:15749019 |
Comment | GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7 |
Status of entry | # |
Expression range: | 4.43 to 296.7 |
Mean expression: | 53.61 ± 26.87 |
Median expression: | 48.16 |