HGNC approved symbol | VPS72 |
HGNC ID | HGNC:11644 |
HGNC approved name | vacuolar protein sorting 72 homolog (S. cerevisiae) |
Entrez gene ID | GeneID:6944 (SSTAR profile) |
UniProt AC (human) | Q15906 |
UniProt ID (human) | VPS72_HUMAN |
Pfam domains | YL1 PF05764 (7-212) YL1_C PF08265 (291-319) |
MGI symbol | Vps72 |
MGI ID | MGI:1202305 |
UniProt AC (mouse) | Q62481 |
UniProt ID (mouse) | VPS72_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:14966270 |
Protein complex | NuA4, NuA4-related complex |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:14966270 |
Comment | The YL1 =VPS72 protein is a subunit of the TRRAP/TIP60 HAT complex. The YL1 protein is also present in cells as a subunit of the previously uncharacterized mammalian SRCAP complex, which bears a striking similarity to the S. cerevisiae SWR1 chromatin remodeling complex. |
Status of entry | # |
Expression range: | 1.35 to 233.91 |
Mean expression: | 40.63 ± 20.53 |
Median expression: | 36.84 |