HGNC approved symbol | WHSC1 |
HGNC ID | HGNC:12766 |
HGNC approved name | Wolf-Hirschhorn syndrome candidate 1 |
Entrez gene ID | GeneID:7468 (SSTAR profile) |
UniProt AC (human) | O96028 |
UniProt ID (human) | NSD2_HUMAN |
Pfam domains | PWWP PF00855 (221-299, 881-972) HMG_box PF00505 (454-505) domain PF23011 (668-712, 1241-1284) domain PF22908 (716-763) domain PF23004 (764-816) PHD PF00628 (834-872) AWS PF17907 (1022-1060) SET PF00856 (1073-1180) C5HCH PF17982 (1284-1328) |
MGI symbol | Whsc1 |
MGI ID | MGI:1276574 |
UniProt AC (mouse) | Q8BVE8 |
UniProt ID (mouse) | NSD2_MOUSE |
HGNC gene family tag | PHF |
HGNC gene family description | Zinc fingers, PHD-type |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:18172012 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K27 |
Product | H3K27me |
PMID for information on target | PMID:18172012 |
Comment | Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity. |
Status of entry | # |
Expression range: | 0.0 to 100.92 |
Mean expression: | 12.74 ± 9.12 |
Median expression: | 10.96 |