HGNC approved symbol | WSB2 |
HGNC ID | HGNC:19222 |
HGNC approved name | WD repeat and SOCS box containing 2 |
Entrez gene ID | GeneID:55884 (SSTAR profile) |
UniProt AC (human) | Q9NYS7 |
UniProt ID (human) | WSB2_HUMAN |
Pfam domains | WD40 PF00400 (145-182, 188-225, 231-267, 289-320, 338-360) SOCS_box PF07525 (367-401) |
MGI symbol | Wsb2 |
MGI ID | MGI:2144041 |
UniProt AC (mouse) | O54929 |
UniProt ID (mouse) | WSB2_MOUSE |
HGNC gene family tag | WDR |
HGNC gene family description | WD repeat domain containing |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:21070969 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | # |
Comment | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, including histones. (Annotated by similarity). |
Status of entry | # |
Expression range: | 0.0 to 327.37 |
Mean expression: | 54.3 ± 36.01 |
Median expression: | 46.22 |