| HGNC approved symbol | YEATS2 |
| HGNC ID | HGNC:25489 |
| HGNC approved name | YEATS domain containing 2 |
| Entrez gene ID | GeneID:55689 (SSTAR profile) |
| UniProt AC (human) | Q9ULM3 |
| UniProt ID (human) | YETS2_HUMAN |
| Pfam domains | YEATS PF03366 (230-310) domain PF22951 (1144-1241) |
| MGI symbol | Yeats2 |
| MGI ID | MGI:2447762 |
| UniProt AC (mouse) | Q3TUF7 |
| UniProt ID (mouse) | YETS2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone chaperone |
| Modification | # |
| PMID for information on function | PMID:18838386, 29057918 |
| Protein complex | ATAC |
| Target molecule | histone |
| Target entity | H3K27ac |
| Product | # |
| PMID for information on target | PMID:18838386, 29057918 |
| Comment | A YEATS2-NC2beta histone fold module that interacts with the TATA-binding protein (TBP) and negatively regulates transcription when recruited to a promoter. The p38 kinase-interacting protein (p38IP/FAM48A) is a novel component of STAGA with distant similarity to yeast Spt20.YEATS2 as a histone H3K27ac reader that regulates a transcriptional program essential for NSCLC tumorigenesis. |
| Status of entry | # |
| Expression range: | 3.64 to 220.11 |
| Mean expression: | 29.29 ± 20.3 |
| Median expression: | 23.91 |