HGNC approved symbol | ZBTB16 |
HGNC ID | HGNC:12930 |
HGNC approved name | zinc finger and BTB domain containing 16 |
Entrez gene ID | GeneID:7704 (SSTAR profile) |
UniProt AC (human) | Q05516 |
UniProt ID (human) | ZBT16_HUMAN |
Pfam domains | BTB PF00651 (25-124) zf-C2H2_6 PF13912 (461-483, 518-540) zf-C2H2 PF00096 (490-512, 546-568, 574-596) domain PF12874 (630-652) |
MGI symbol | Zbtb16 |
MGI ID | MGI:103222 |
UniProt AC (mouse) | # |
UniProt ID (mouse) | # |
HGNC gene family tag | ZBTB, ZNF, BTBD |
HGNC gene family description | Zinc fingers, C2H2-type, BTB/POZ domain containing |
Function | Histone modification erase cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:9627120, PMID:15467736 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | # |
Comment | Recruites SMRT-mSin3-HDAC co-repressor complex. The repressive domains of PLZF function by recruiting N-CoR/Sin3A co-repressor complexes which in turn recruit histone deacetylases (HDACs). |
Status of entry | # |
Expression range: | 0.0 to 385.22 |
Mean expression: | 16.35 ± 34.07 |
Median expression: | 1.48 |