| HGNC approved symbol | HGNC ID | HGNC approved name | Entrez gene ID | UniProt AC (human) | UniProt ID (human) | Pfam domains | MGI symbol | MGI ID | UniProt AC (mouse) | UniProt ID (mouse) | HGNC gene family tag | HGNC gene family description | Function | Modification | PMID for information on function | Protein complex | Target molecule | Target entity | Product | PMID for information on target | Comment | Status of entry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
NAT10
(details) |
29830 | N-acetyltransferase 10 (GCN5-related) | 55226 | Q9H0A0 | NAT10_HUMAN | TmcA_N PF08351 9-201, Helicase_RecD PF05127 282-486, GNAT_acetyltr_2 PF13718 529-753, tRNA_bind_2 PF13725 763-974 | Nat10 | 2138939 | Q8K224 | NAT10_MOUSE | # | # | Histone modification write | Histone acetylation | 14592445 | # | histone | # | # | 14592445 | hALP =NAT10 can specifically acetylate free histones in vitro. hALP may influence the activity of histone acetylation and possibly up-regulate telomerase activity through transactivation of hTERT promoter. | # |
|
NAT10
(details) |
29830 | N-acetyltransferase 10 | 55226 | Q9H0A0 | NAT10_HUMAN | TmcA_N PF08351 9-201, Helicase_RecD PF05127 282-486, GNAT_acetyltr_2 PF13718 529-753, tRNA_bind_2 PF13725 763-974 | Nat10 | 2138939 | Q8K224 | NAT10_MOUSE | GNAT | GCN5 related N-acetyltransferase | RNA modification | RNA acetylation | 30449621 | # | RNA | C of mRNA | ac4C | 30449621 | Regulates mRNA stabiility and therefore translation efficiency | New |