Protein complex info
Complex group nameHAT
Complex nameMSL histone acetyltransferase complex
Genes in complexMSL1#407, MSL2#408, KAT8#329
Alternative names
Proteins involvedMSL1, MSL2, MSL3, KAT8 (hMOF)
Uniprot IDs of involved proteins
MSL1_HUMAN, MSL2_HUMAN, M3SL1_HUMAN, KAT8_HUMAN
PMID for reference on complex compositionPMID:16227571
Functionhistone acetylation complex
PMID for reference on functionPMID:16227571, PMID:17694080
Target molecule typehistone
Specific targetH4
ProductH4K16Ac
Target UniProt IDH4_HUMAN
PMID for reference on targets and productsPMID:16227571
CommentResponsible for genome-wide H4K16 acetylation. Affects chromatin organization and regulates transcription. Involved in regulation of cell cycle progression, DNA damage repair and apoptosis.
Status of entryNew