Complex group name | HAT |
Complex name | MSL histone acetyltransferase complex |
Genes in complex | MSL1#407, MSL2#408, KAT8#329 |
Alternative names | |
Proteins involved | MSL1, MSL2, MSL3, KAT8 (hMOF) |
Uniprot IDs of involved proteins | MSL1_HUMAN, MSL2_HUMAN, M3SL1_HUMAN, KAT8_HUMAN |
PMID for reference on complex composition | PMID:16227571 |
Function | histone acetylation complex |
PMID for reference on function | PMID:16227571, PMID:17694080 |
Target molecule type | histone |
Specific target | H4 |
Product | H4K16Ac |
Target UniProt ID | H4_HUMAN |
PMID for reference on targets and products | PMID:16227571 |
Comment | Responsible for genome-wide H4K16 acetylation. Affects chromatin organization and regulates transcription. Involved in regulation of cell cycle progression, DNA damage repair and apoptosis. |
Status of entry | New |