Protein complex info
Complex group nameMis18
Complex nameMis18
Genes in complexMIS18A#395, OIP5#452, MIS18BP1#396
Alternative names#
Proteins involvedMIS18A, OIP5, MIS18BP1
Uniprot IDs of involved proteins
PMID for reference on complex compositionPMID:22516971
FunctionChromatin remodeling
PMID for reference on functionPMID:22516971, PMID:26942680
Target molecule typehistone
Specific targetCENPA
Target UniProt ID#
PMID for reference on targets and productsPMID:22516971
CommentRegulates CENPA recruitment to centromeres and thereby normal chromosome segregation during mitosis. Interacts with DNMT3A/3B and provides it`s centromeric localization regulating epigenetic states of centromeric chromatin. Provides access of CENPA-specific chaperone HJURP to centromeres.
Status of entryNew