| Complex group name | CAF-1 |
| Complex name | CAF-1 |
| Genes in complex | CHAF1A#129, CHAF1B#130, RBBP4#547 |
| Alternative names | # |
| Proteins involved | RBBP4, CHAF1B and CHAF1A |
| Uniprot IDs of involved proteins | CAF1A_HUMAN, CAF1B_HUMAN, RBBP4_HUMAN |
| PMID for reference on complex composition | PMID:8858152 |
| Function | chromatin assembly complex |
| PMID for reference on function | PMID:8858152 |
| Target molecule type | histone |
| Specific target | H3, H4 |
| Product | # |
| Target UniProt ID | H31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN, H4_HUMAN |
| PMID for reference on targets and products | PMID:8858152 |
| Comment | Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. |
| Status of entry | # |