Complex group name | MLL |
Complex name | COMPASS-like MLL1,2 |
Genes in complex | ASH2L#43, DPY30#189, HCFC1#257, KAT8#329, (KMT2A#352|KMT2D#355), MEN1#385, RBBP5#548, WDR5#764 |
Alternative names | # |
Proteins involved | MLL1 or MLL2, MOF, Menin, ASH2L, DRY30, HCF1, RBBP5, WDR5 |
Uniprot IDs of involved proteins | ASH2L_HUMAN, DPY30_HUMAN, HCFC1_HUMAN, KAT8_HUMAN, (KMT2A_HUMAN|KMT2D_HUMAN), MEN1_HUMAN, RBBP5_HUMAN, WDR5_HUMAN |
PMID for reference on complex composition | PMID:22108599 |
Function | histone methylation complex, histone acetylation complex |
PMID for reference on function | PMID:22108599 |
Target molecule type | histone |
Specific target | H4K16 |
Product | H4K16ac |
Target UniProt ID | H4_HUMAN |
PMID for reference on targets and products | PMID:22108599 |
Comment | Hox-family gene regulator; tumor supressor activity. |
Status of entry | # |