Complex group name | HAT |
Complex name | NSL |
Genes in complex | HCFC1#257, KANSL1#320, KANSL2#321, KANSL3#322, KAT8#329, MCRS1#381, PHF20#485, OGT#451, WDR5#764 |
Alternative names | # |
Proteins involved | MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1 |
Uniprot IDs of involved proteins | HCFC1_HUMAN, KANL1_HUMAN, KANL2_HUMAN, KANL3_HUMAN, KAT8_HUMAN, MCRS1_HUMAN, PHF20_HUMAN, OGT1_HUMAN, WDR5_HUMAN |
PMID for reference on complex composition | PMID:20018852 |
Function | histone acetylation complex |
PMID for reference on function | PMID:20018852 |
Target molecule type | histone |
Specific target | H4K16 |
Product | H4K16ac |
Target UniProt ID | H4_HUMAN |
PMID for reference on targets and products | PMID:20018852 |
Comment | It is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. |
Status of entry | # |