| Complex group name | HAT |
| Complex name | NuA4 |
| Genes in complex | ACTL6A#4, ACTB#3, BRD8#81, DMAP1#175, MEAF6#383, EP400#211, EPC1#212, ING3#304, KAT5#325, MORF4L1#400, MORF4L2#401, MRGBP#405, RUVBL1#584, RUVBL2#585, TRRAP#723, VPS72#761, YEATS4#773 |
| Alternative names | # |
| Proteins involved | KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6 |
| Uniprot IDs of involved proteins | ACL6A_HUMAN, ACTB_HUMAN, BRD8_HUMAN, DMAP1_HUMAN, EAF6_HUMAN, EP400_HUMAN, EPC1_HUMAN, ING3_HUMAN, KAT5_HUMAN, MO4L1_HUMAN, MO4L2_HUMAN, MRGBP_HUMAN, RUVB1_HUMAN, RUVB2_HUMAN, TRRAP_HUMAN, VPS72_HUMAN, YETS4_HUMAN |
| PMID for reference on complex composition | PMID:14966270, PMID:16387653 |
| Function | histone acetylation complex |
| PMID for reference on function | PMID:14966270 |
| Target molecule type | histone |
| Specific target | H4, H2A |
| Product | H4ac, H2Aac |
| Target UniProt ID | H2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN, H4_HUMAN |
| PMID for reference on targets and products | PMID:14966270 |
| Comment | Is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. |
| Status of entry | # |