Complex group name | HDAC |
Complex name | NuRD |
Genes in complex | CHD3#134, CHD4#135, HDAC1#259, HDAC2#262, KDM1A#330, MBD2#372, MBD3#373, MTA1#411, MTA2#412, MTA3#413, (GATAD2A#247|GATAD2B#248), RBBP4#547, RBBP7#549 |
Alternative names | NRD, CHD3/CHD4 |
Proteins involved | HDAC1, HDAC2, RBBP4, RBBP7, MTA1, MTA2, MTA3, MBD2, MBD3, p66, CHD3 or CHD4, LSD1 |
Uniprot IDs of involved proteins | CHD3_HUMAN, CHD4_HUMAN, HDAC1_HUMAN, HDAC2_HUMAN, KDM1A_HUMAN, MBD2_HUMAN, MBD3_HUMAN, MTA1_HUMAN, MTA2_HUMAN, MTA3_HUMAN, (P66A_HUMAN|P66B_HUMAN), RBBP4_HUMAN, RBBP7_HUMAN |
PMID for reference on complex composition | PMID:19644445, PMID:10589671, PMID:17289569, PMID:22108599 |
Function | histone deacetylation complex, histone methylation complex, chromatin remodeling complex |
PMID for reference on function | PMID:10589671, PMID:22108599 |
Target molecule type | histone |
Specific target | H3 |
Product | # |
Target UniProt ID | H31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN |
PMID for reference on targets and products | PMID:11850414 |
Comment | The nucleosome remodeling and histone deacetylation complex. |
Status of entry | # |