Complex group name | SWI/SNF |
Complex name | PBAF |
Genes in complex | (ACTL6A#4|ACTL6B#5), ACTB#3, (ARID1A#33|ARID1B#34), ARID2#35, SMARCA4#629, SMARCE1#639, SMARCC1#634, SMARCC2#635, SMARCD1#636, SMARCD2#637, SMARCD3#638?, SMARCB1#633, PBRM1#466 |
Alternative names | SWI/SNF-B |
Proteins involved | SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin |
Uniprot IDs of involved proteins | (ACL6A_HUMAN|ACL6B_HUMAN), ACTB_HUMAN, (ARI1A_HUMAN|ARI1B_HUMAN), ARID2_HUMAN, SMCA4_HUMAN, SMCE1_HUMAN, SMRC1_HUMAN, SMRC2_HUMAN, SMRD1_HUMAN, SMRD2_HUMAN, SMRD3_HUMAN?, SNF5_HUMAN, PB1_HUMAN |
PMID for reference on complex composition | PMID:11078522, PMID:11780067, PMID:15985610 |
Function | chromatin remodeling complex |
PMID for reference on function | PMID:11780067 |
Target molecule type | chromatin |
Specific target | # |
Product | # |
Target UniProt ID | # |
PMID for reference on targets and products | # |
Comment | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. |
Status of entry | # |