Complex group name | DUB |
Complex name | PR-DUB |
Genes in complex | ASXL1#44, BAP1#63 |
Alternative names | # |
Proteins involved | BAP1 and ASXL1 |
Uniprot IDs of involved proteins | ASXL1_HUMAN, BAP1_HUMAN |
PMID for reference on complex composition | PMID:20436459 |
Function | histone deubiquitination complex |
PMID for reference on function | PMID:20436459 |
Target molecule type | histone |
Specific target | H2AK119 |
Product | H2AK119ub1 |
Target UniProt ID | H2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN |
PMID for reference on targets and products | PMID:20436459 |
Comment | A complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). |
Status of entry | # |