Complex group name | HAT |
Complex name | Pol2 elongator |
Genes in complex | IKBKAP#299, ELP2#204, ELP3#205, ELP4#206, ELP5#207, ELP6#208 |
Alternative names | RNA polymerase II elongator complex |
Proteins involved | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6 |
Uniprot IDs of involved proteins | ELP1_HUMAN, ELP2_HUMAN, ELP3_HUMAN, ELP4_HUMAN, ELP5_HUMAN, ELP6_HUMAN |
PMID for reference on complex composition | PMID:11714725, PMID:11818576 |
Function | histone acetylation complex |
PMID for reference on function | PMID:11714725 |
Target molecule type | histone |
Specific target | H3, H4 |
Product | H3ac, H4ac |
Target UniProt ID | H31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN, H4_HUMAN |
PMID for reference on targets and products | PMID:11714725 |
Comment | A histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Original name "RNA polymerase II elongator complex". |
Status of entry | # |