Protein complex info
Complex group nameHAT
Complex namePol2 elongator
Genes in complexIKBKAP, ELP2, ELP3, ELP4, ELP5, ELP6
Alternative namesRNA polymerase II elongator complex
Proteins involvedELP1, ELP2, ELP3, ELP4, ELP5, ELP6
Uniprot IDs of involved proteins
ELP1_HUMAN, ELP2_HUMAN, ELP3_HUMAN, ELP4_HUMAN, ELP5_HUMAN, ELP6_HUMAN
PMID for reference on complex compositionPMID:11714725, PMID:11818576
Functionhistone acetylation complex
PMID for reference on functionPMID:11714725
Target molecule typehistone
Specific targetH3, H4
ProductH3ac, H4ac
Target UniProt IDH31_HUMAN, H31T_HUMAN, H32_HUMAN, H33_HUMAN, H3C_HUMAN, H4_HUMAN
PMID for reference on targets and productsPMID:11714725
CommentA histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Original name "RNA polymerase II elongator complex".
Status of entry#