Complex group name | PcG and PcG-like |
Complex name | RING2-L3MBTL2 |
Genes in complex | CBX3#99, E2F6#193, (HDAC1#259|HDAC2#262), L3MBTL2#358, MGA#392, PCGF6#471, (RING1#568|RNF2#572), (RYBP#586|YAF2#771), TFDP1#702, WDR5#764 |
Alternative names | PRC1.6 |
Proteins involved | RING2, RYBP/YAF2, L3MBTL2, E2F6, PCGF6, CBX3, HDAC1/HDAC2, Dp-1, WDR5, MGA |
Uniprot IDs of involved proteins | CBX3_HUMAN, E2F6_HUMAN, (HDAC1_HUMAN|HDAC2_HUMAN), LMBL2_HUMAN, MGAP_HUMAN, PCGF6_HUMAN, (RING1_HUMAN|RING2_HUMAN), (RYBP_HUMAN|YAF2_HUMAN), TFDP1_HUMAN, WDR5_HUMAN |
PMID for reference on complex composition | PMID:22325352, PMID:24217316 |
Function | Polycomb like complex |
PMID for reference on function | PMID:22325352, PMID:24217316 |
Target molecule type | histone |
Specific target | H2AK119 |
Product | H2AK119ub1 |
Target UniProt ID | H2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN |
PMID for reference on targets and products | # |
Comment | # |
Status of entry | # |