Complex group name | HAT |
Complex name | SAGA |
Genes in complex | ATXN7L3#56, ATXN7#55, ENY2#209, KAT2A#323, SUPT3H#665, TAF10#679, TRRAP#723, USP22#751 |
Alternative names | # |
Proteins involved | ATXN7, ATXN7L3, ENY2, KAT2A, SUPT3H, TAF10, TRRAP and USP22 |
Uniprot IDs of involved proteins | AT7L3_HUMAN, ATX7_HUMAN, ENY2_HUMAN, KAT2A_HUMAN, SUPT3_HUMAN, TAF10_HUMAN, TRRAP_HUMAN, UBP22_HUMAN |
PMID for reference on complex composition | PMID:10637607, PMID:17337012 |
Function | histone acetylation complex, histone deubiquitination complex |
PMID for reference on function | PMID:18206972 |
Target molecule type | histone |
Specific target | H2A, H2B, H2Aub, H2Bub |
Product | H2Aac, H2Bac, H2A, H2B |
Target UniProt ID | H2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN, H2B1A_HUMAN, H2B1B_HUMAN, H2B1C_HUMAN, H2B1D_HUMAN, H2B1H_HUMAN, H2B1J_HUMAN, H2B1K_HUMAN, H2B1L_HUMAN, H2B1M_HUMAN, H2B1N_HUMAN, H2B1O_HUMAN, H2B2C_HUMAN, H2B2D_HUMAN, H2B2E_HUMAN, H2B2F_HUMAN, H2B3B_HUMAN, H2BFM_HUMAN, H2BFS_HUMAN, H2BWT_HUMAN |
PMID for reference on targets and products | PMID:18206972 |
Comment | Histone acetylation (HAT) complex, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. |
Status of entry | # |