| Complex group name | SRCAP |
| Complex name | SRCAP |
| Genes in complex | ACTL6A#4, ACTR6#8, DMAP1#175, SRCAP#652, RUVBL1#584, RUVBL2#585, YEATS4#773, ZNHIT1#799 |
| Alternative names | # |
| Proteins involved | SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1 |
| Uniprot IDs of involved proteins | ACL6A_HUMAN, ARP6_HUMAN, DMAP1_HUMAN, SRCAP_HUMAN, RUVB1_HUMAN, RUVB2_HUMAN, YETS4_HUMAN, ZNHI1_HUMAN |
| PMID for reference on complex composition | PMID:15647280 |
| Function | chromatin remodeling complex |
| PMID for reference on function | PMID:15647280 |
| Target molecule type | chromatin, histone |
| Specific target | histone dimers containing H2B and H2A.Z |
| Product | mononucleosomes reconstituted with recombinant H2A,H2B,H3,H4 |
| Target UniProt ID | H2AZ_HUMAN, H2B1A_HUMAN, H2B1B_HUMAN, H2B1C_HUMAN, H2B1D_HUMAN, H2B1H_HUMAN, H2B1J_HUMAN, H2B1K_HUMAN, H2B1L_HUMAN, H2B1M_HUMAN, H2B1N_HUMAN, H2B1O_HUMAN, H2B2C_HUMAN, H2B2D_HUMAN, H2B2E_HUMAN, H2B2F_HUMAN, H2B3B_HUMAN, H2BFM_HUMAN, H2BFS_HUMAN, H2BWT_HUMAN |
| PMID for reference on targets and products | PMID:16634648, PMID:17617668 |
| Comment | Mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. SRCAP-containing complex supports ATP-dependent exchange of histone dimers containing H2B and H2A.Z into mononucleosomes reconstituted with recombinant H2A, H2B, H3, and H4. |
| Status of entry | # |