| Complex group name | WMM |
| Complex name | WMM |
| Genes in complex | METTL3#390, METTL14#387, WTAP#770, ZC3H13#783, CBLL1#96, VIRMA#760 |
| Alternative names | WTAP-METTL3-METTL14 N6-adenosine-methyltransferase complex, WTAP-METTL3-METTL14 methyltransferase complex, WMM methyltransferase complex |
| Proteins involved | METTL3, METTL14, WTAP, ZC3H13, CBLL1, VIRMA |
| Uniprot IDs of involved proteins | MTA70_HUMAN, MET14_HUMAN, FL2D_HUMAN, ZC3HD_HUMAN, HAKAI_HUMAN, VIR_HUMAN |
| PMID for reference on complex composition | PMID:29348140 |
| Function | RNA methylation |
| PMID for reference on function | PMID:24316715 |
| Target molecule type | RNA, DNA |
| Specific target | A of RNA, A of DNA |
| Product | m6A |
| Target UniProt ID | # |
| PMID for reference on targets and products | PMID:27281194 |
| Comment | Regulates processes dependent on RNA stability as m6A methylation leads to RNA degradation. Controls cell differentiation of embryonic and hematopoietic stem cells by destabilization of transcripts. Involved in response to DNA-damage. Mediates random X-inactivation by methylation of Xist-RNA. Marks primary microRNAs for processing. Promotes translation. |
| Status of entry | New |