Complex group name | SWI/SNF |
Complex name | nBAF |
Genes in complex | ACTL6B#5, ACTB#3, (ARID1A#33|ARID1B#34), DPF1#185, DPF3#187, SMARCA2#628, SMARCA4#629, SMARCE1#639, SMARCC1#634, SMARCC2#635, SMARCD1#636, SMARCD3#638, SMARCB1#633 |
Alternative names | neuron-specific chromatin remodeling complex |
Proteins involved | ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B and actin |
Uniprot IDs of involved proteins | ACL6B_HUMAN, ACTB_HUMAN, (ARI1A_HUMAN|ARI1B_HUMAN), DPF1_HUMAN, DPF3_HUMAN, SMCA2_HUMAN, SMCA4_HUMAN, SMCE1_HUMAN, SMRC1_HUMAN, SMRC2_HUMAN, SMRD1_HUMAN, SMRD3_HUMAN, SNF5_HUMAN |
PMID for reference on complex composition | PMID:10078207, PMID:11078522, PMID:18765789, by similarity |
Function | chromatin remodeling complex |
PMID for reference on function | PMID:11078522 |
Target molecule type | chromatin |
Specific target | # |
Product | # |
Target UniProt ID | # |
PMID for reference on targets and products | # |
Comment | The neuron-specific chromatin remodeling complex. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. |
Status of entry | # |