| HGNC approved symbol | HGNC ID | HGNC approved name | Entrez gene ID | UniProt AC (human) | UniProt ID (human) | Pfam domains | MGI symbol | MGI ID | UniProt AC (mouse) | UniProt ID (mouse) | HGNC gene family tag | HGNC gene family description | Function | Modification | PMID for information on function | Protein complex | Target molecule | Target entity | Product | PMID for information on target | Comment | Status of entry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
CHD1
(details) |
1915 | chromodomain helicase DNA binding protein 1 | 1105 | O14646 | CHD1_HUMAN | Chromo PF00385 313-351 389-443, SNF2-rel_dom PF00176 482-764, Helicase_C PF00271 789-902, CDH1_2_SANT_HL1 PF18375 1124-1211, CHD1-like_C PF13907 1409-1500 | Chd1 | 88393 | P40201 | CHD1_MOUSE | # | # | Chromatin remodeling | # | 12592387 | # | DNA | # | # | 12592387 | These proteins have a DNA-binding domain as well as a chromodomain motif that can directly effect chromatin structure and gene transcription. There are currently four known members of this gene family in humans (CHD1–CHD4). | # |
|
CHD2
(details) |
1917 | chromodomain helicase DNA binding protein 2 | 1106 | O14647 | CHD2_HUMAN | Chromo PF00385 300-338 378-447, SNF2-rel_dom PF00176 487-767, Helicase_C PF00271 792-905, CDH1_2_SANT_HL1 PF18375 1129-1219, CHD1-like_C PF13907 1465-1553 | Chd2 | 2448567 | E9PZM4 | CHD2_MOUSE | # | # | Chromatin remodeling | # | 12592387 | # | DNA | # | # | 12592387 | These proteins have a DNA-binding domain as well as a chromodomain motif that can directly effect chromatin structure and gene transcription. There are currently four known members of this gene family in humans (CHD1–CHD4). | # |