| HGNC approved symbol | HGNC ID | HGNC approved name | Entrez gene ID | UniProt AC (human) | UniProt ID (human) | Pfam domains | MGI symbol | MGI ID | UniProt AC (mouse) | UniProt ID (mouse) | HGNC gene family tag | HGNC gene family description | Function | Modification | PMID for information on function | Protein complex | Target molecule | Target entity | Product | PMID for information on target | Comment | Status of entry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
MBNL1
(details) |
6923 | Muscleblind-like protein 1 (Triplet-expansion RNA-binding protein) | 4154 | Q9NR56 | MBNL1_HUMAN | zf-CCCH_2 PF14608 19-39, domain PF22628 48-86 216-253, zf-CCCH PF00642 183-205 | Mbnl1 | 1928482 | Q9JKP5 | MBNL1_MOUSE | ZC3H | Zinc fingers CCCH-type | RNA modification | Alternative splicing | 16946708, 19470458, 15257297 | # | RNA | mRNA | # | 16946708, 19470458, 15257297 | Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonistic regulator with CELF proteins. | New |
|
RBM4
(details) |
9901 | RNA-binding protein 4 (Lark homolog) (hLark) (RNA-binding motif protein 4) (RNA-binding motif protein 4a) | 5936 | Q9BWF3 | RBM4_HUMAN | RRM_1 PF00076 4-65 80-142, zf-CCHC PF00098 161-176 | Rbm4 | 1100865 | Q8C7Q4 | RBM4_MOUSE | RBM | RNA binding motif containing | RNA modification | Alternative splicing | 16777844, 21518792 | # | RNA | RNA | # | 16777844, 21518792 | Modulates alternative 5'-splice site and exon selection. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation | New |