| HGNC approved symbol | RBBP7 |
| HGNC ID | HGNC:9890 |
| HGNC approved name | retinoblastoma binding protein 7 |
| Entrez gene ID | GeneID:5931 (SSTAR profile) |
| UniProt AC (human) | Q16576 |
| UniProt ID (human) | RBBP7_HUMAN |
| Pfam domains | CAF1C_H4-bd PF12265 (18-87) WD40 PF00400 (172-205, 220-255, 264-301, 308-345, 366-402) |
| MGI symbol | Rbbp7 |
| MGI ID | MGI:1194910 |
| UniProt AC (mouse) | Q60973 |
| UniProt ID (mouse) | RBBP7_MOUSE |
| HGNC gene family tag | WDR |
| HGNC gene family description | WD repeat domain containing |
| Function | Histone chaperone |
| Modification | # |
| PMID for information on function | PMID:18571423 |
| Protein complex | NuRF, NuRD, mSin3A, core HDAC, mSin3A-like complex, PRC2 |
| Target molecule | histone |
| Target entity | H4 |
| Product | # |
| PMID for information on target | PMID:18571423 |
| Comment | RbAp46 and RbAp48 (pRB-associated proteins p46 and p48, also known as RBBP7 and RBBP4, respectively) are highly homologous histone chaperones that play key roles in establishing and maintaining chromatin structure. When a histone H3/H4 dimer (or tetramer) binds to RbAp46 or RbAp48, helix 1 of histone H4 unfolds to interact with the histone chaperone. |
| Status of entry | # |
| Expression range: | 9.34 to 444.52 |
| Mean expression: | 76.03 ± 45.62 |
| Median expression: | 65.32 |