| HGNC approved symbol | TAF5 |
| HGNC ID | HGNC:11539 |
| HGNC approved name | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| Entrez gene ID | GeneID:6877 (SSTAR profile) |
| UniProt AC (human) | Q15542 |
| UniProt ID (human) | TAF5_HUMAN |
| Pfam domains | TFIID_NTD2 PF04494 (210-340) WD40 PF00400 (466-498, 535-571, 577-612, 618-655, 660-697, 703-739) |
| MGI symbol | Taf5 |
| MGI ID | MGI:2442144 |
| UniProt AC (mouse) | Q8C092 |
| UniProt ID (mouse) | TAF5_MOUSE |
| HGNC gene family tag | WDR |
| HGNC gene family description | WD repeat domain containing |
| Function | Histone modification write cofactor |
| Modification | Histone acetylation |
| PMID for information on function | PMID:10373431 |
| Protein complex | TFTC-HAT |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:10373431 |
| Comment | TFTC, similar to other TBP-free TAFII complexes (yeast SAGA, hSTAGA, and hPCAF) contains the acetyltransferase hGCN5 and is able to acetylate histones in both a free and a nucleosomal context. A monoclonal antibody raised against hTAFII100 recognized hTAFII100=TAF5 not only in TFTC, but detected also a weak band in the PCAF complex. |
| Status of entry | # |
| Expression range: | 0.0 to 30.01 |
| Mean expression: | 5.33 ± 3.77 |
| Median expression: | 4.36 |