HGNC approved symbol | EIF4A3 |
HGNC ID | HGNC:18683 |
HGNC approved name | Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed] |
Entrez gene ID | GeneID:9775 (SSTAR profile) |
UniProt AC (human) | P38919 |
UniProt ID (human) | IF4A3_HUMAN |
Pfam domains | DEAD PF00270 (63-225) Helicase_C PF00271 (264-372) |
MGI symbol | EIf4A3 |
MGI ID | MGI:1923731 |
UniProt AC (mouse) | Q91VC3 |
UniProt ID (mouse) | IF4A3_MOUSE |
HGNC gene family tag | DDX |
HGNC gene family description | DEAD-box helicases |
Function | RNA modification |
Modification | Alternative splicing |
PMID for information on function | PMID:22203037 |
Protein complex | # |
Target molecule | RNA |
Target entity | mRNA |
Product | # |
PMID for information on target | PMID:22203037 |
Comment | Production of the proapoptotic Bcl-x(S) splice variant. |
Status of entry | New |
Expression range: | 10.78 to 182.83 |
Mean expression: | 42.8 ± 23.41 |
Median expression: | 37.82 |