| HGNC approved symbol | ING1 |
| HGNC ID | HGNC:6062 |
| HGNC approved name | inhibitor of growth family, member 1 |
| Entrez gene ID | GeneID:3621
(SSTAR profile) |
| UniProt AC (human) | Q9UK53 |
| UniProt ID (human) | ING1_HUMAN |
| Pfam domains | ING PF12998 (186-254) |
| MGI symbol | Ing1 |
| MGI ID | MGI:1349481 |
| UniProt AC (mouse) | Q9QXV3 |
| UniProt ID (mouse) | ING1_MOUSE |
| HGNC gene family tag | PHF |
| HGNC gene family description | Zinc fingers, PHD-type |
| Function | Histone modification read |
| Modification | # |
| PMID for information on function | PMID:18533182 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K4me3 |
| Product | # |
| PMID for information on target | PMID:18533182 |
| Comment | Both DNA repair and apoptotic activities of ING1 require the interaction of the C-terminal plant homeodomain (PHD) finger with histone H3 trimethylated at Lys4 (H3K4me3). The ING1 PHD finger recognizes methylated H3K4 but not other histone modifications as revealed by peptide microarrays. |
| Status of entry | # |