| HGNC approved symbol | ING5 |
| HGNC ID | HGNC:19421 |
| HGNC approved name | inhibitor of growth family, member 5 |
| Entrez gene ID | GeneID:84289
(SSTAR profile) |
| UniProt AC (human) | Q8WYH8 |
| UniProt ID (human) | ING5_HUMAN |
| Pfam domains | ING PF12998 (6-107) |
| MGI symbol | Ing5 |
| MGI ID | MGI:1922816 |
| UniProt AC (mouse) | Q9D8Y8 |
| UniProt ID (mouse) | ING5_MOUSE |
| HGNC gene family tag | PHF |
| HGNC gene family description | Zinc fingers, PHD-type |
| Function | Histone modification read |
| Modification | # |
| PMID for information on function | PMID:18623064 |
| Protein complex | HBO1, MOZ/MORF |
| Target molecule | histone |
| Target entity | H3K4me3, H3K4me2 |
| Product | # |
| PMID for information on target | PMID:18623064 |
| Comment | Crystal structure of the ING5 PHD finger in complex with its histone target (H3K4me3). Binding affinities for unmodified, mono-, di-, and tri-methylated histone peptides showed that both full-length ING5 and methylated H3K4 are essential for the acetyltransferase activity of the MOZ/MORF and HBO1 complexes. |
| Status of entry | # |