HGNC approved symbol | MBNL3 |
HGNC ID | HGNC:20564 |
HGNC approved name | Muscleblind-like protein 3 (Cys3His CCG1-required protein) (Muscleblind-like X-linked protein) (Protein HCHCR) |
Entrez gene ID | GeneID:55796 (SSTAR profile) |
UniProt AC (human) | Q9NUK0 |
UniProt ID (human) | MBNL3_HUMAN |
Pfam domains | zf-CCCH_2 PF14608 (20-40) domain PF22628 (49-87, 211-248) zf-CCCH_4 PF18044 (179-200) |
MGI symbol | Mbnl3 |
MGI ID | MGI:2444912 |
UniProt AC (mouse) | Q8R003 |
UniProt ID (mouse) | MBNL3_MOUSE |
HGNC gene family tag | ZC3H |
HGNC gene family description | Zinc fingers CCCH-type |
Function | RNA modification |
Modification | Alternative splicing |
PMID for information on function | PMID:15257297 |
Protein complex | # |
Target molecule | RNA |
Target entity | mRNA |
Product | # |
PMID for information on target | PMID:15257297 |
Comment | Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonistic regulator with CELF proteins. |
Status of entry | New |
Expression range: | 0.0 to 5453.53 |
Mean expression: | 43.57 ± 315.41 |
Median expression: | 6.37 |